are clickable links to these studies. Research on honokiol has found that it can reduce inflammation in the brain and spinal cord specifically, partly due to its ability to cross the blood-brain barrier (14). Nevertheless, amid the wide range of personalized treatments, there remain a handful of powerful integrative therapies that continue to demonstrate remarkableresults against cancer, regardless of the type or stage. Magnolol inhibited cancer growth and reduced tumor size in vitro. Exercise: Physical activity helps your body blow off steam, but its benefits dont stop there. This not only includes brain disorders like Alzheimers disease but also conditions like stress, anxiety, mood disorders, and depression (23). Standard dosing for magnolia bark is as follows: Decoction (tea made from bark or berries): 3 10g per person/day, Dietary Supplement: 200 800mg per person/day, Relora (Magnolia/Phellodendron supplement): 250mg, 3x/day. This article reviews what it is, its best uses, potential benefits, and side, Suma root has many medicinal uses in folk medicine, but scientific evidence supporting its purported benefits is lacking. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats. Christopher Hobbs, another well-known herbalist, also describes magnolia bark as supportive for inducing sleep. The traditional Chinese wellness therapy methods at Magnolia Spa can relieve you of your stress, tiredness, headaches and muscle pain, as well as alleviate tension in the neck, shoulders, back, arms, legs and feet. Wolf, I., O'Kelly, J., Wakimoto, N., Nguyen, A., Amblard, F., Karlan, B. Y., Arbiser, J. L., & Koeffler, H. P. (2007). His therapy, or "thorapy" as The REAL Bark team calls it . The bark is harvested from April to June where it is then dried in shade. Retrieved from: https://www.henriettes-herb.com/eclectic/dmna/magnolia.html#glau-bot-hist, Ge, L., Zhang, W., Zhou, G., Ma, B., Mo, Q., Chen, Y., & Wang, Y. Magnolia barks scientific name is Magnolia officinalis. So go for a walk, take a bike ride, or dance around the room and let those endorphins kick in. Cortisol is the primary stress hormone in your body. https://doi.org/10.1021/np800494e, Siegel, R. L., Miller, K. D., & Jemal, A. Exercising leads to the release of endorphins, natural feel-good chemicals that combat the effects of stress. There are many different methods and techniques, so keep trying until you find a practice you feel good about. 7 These properties may or may not eventually translate to the treatment or prevention of common bacterial, viral, or fungal infections in people. Additionally, the magnolol appeared to increase the number of times the mice woke up during sleep but decrease the length of time they were awake. It comes from the Magnolia tree famous for its large, dramatic flowers. This article is based on scientific evidence, written by experts and fact checked by our trained editorial staff. https://doi.org/10.2147/OTT.S168887. This makes sense, as its known that GABA(A) receptor activity is closely associated with sleep (29). Therefore, it isn't possible to say if the side effects were due to metformin or pine pollen. And when you pair honokiol with MCP, the antioxidant and anti-inflammatory effects of both increase significantly, offering more stress relief for you. Safety and Toxicology of Magnolol and Honokiol. Once their inner surface turns dark brown or purplish brown, the TCM practitioners steam, roll, and dry them. Overview Magnolia (Magnolia biondii) is a plant found in parts of Asia and North and South America. Modern research shows that it's helpful when treating various conditions like stress-induced anxiety, digestive issues . Multiple published papers on this unique extract demonstrate its effectiveness and safety, including one study showing it works synergistically with MCP. So learning how to manage your stress today may help protect you against that devastating loss of self in the future. summary The bark, leaves, and. For these reasons, galectin-3 is termed, the guardian of the tumor microenvironment.. The overreactions can leave you struggling with autoimmune disease symptoms. Science. Magnolol and honokiol achieve this effect by improving the intestinal movement that helps move digested food through the gastrointestinal tract. Exercise also helps regulate your bodys stress responses so you become less reactive when faced with stressors. Magnolia bark has been used for centuries to treat digestive problems, including nausea, abdominal pain and bloating, diarrhea, and loss of appetite. Beach Animal Rehabilitation Center (BARC) is a one of a kind veterinary clinic, serving Los Angeles and Orange Counties, specializing in rehabilitation for dogs and cats. It is worth checking into magnolia bark if you have been experiencing any of the above indications. A recent study demonstrated that a magnolia/phellodendron bark supplement reduced stress-related eating in 56 moderately-stressed participants. When taken together, the evidence conveys that magnolia bark extract may help with the psycho-affective symptoms of menopause. As part of his commitment to the advancement of integrative medicine, Dr. Eliaz partners with leading research institutes and has co-authored numerous peer-reviewed papers on innovative therapies for immune enhancement, heavy metal toxicity and cancer prevention and treatment. Exception of use under qualified healthcare practitioner supervision. This tree belongs to the Magnoliaceae family and can grow to a mature height from 16 ft up to 80 ft. You can easily identify the magnolia tree from its large and fragrant flowers that often reach 8 inches in diameter. Anticancer research, 30(3), 777783. With strict editorial sourcing guidelines, we only link to academic research institutions, reputable media sites and, when research is available, medically peer-reviewed studies. Chief among them are practicing breathing exercises, particularly the relaxing breath, which I find to be reliable and effective. Neolignans are a type of polyphenol micronutrient in plants. Journal of cellular and molecular medicine, 22(3), 18941908. B, 18(3), 194214. Galectin-3 allows tumor cells to stick together, develop blood supply, metastasize and evade the immune system. Its important to note that the exact mechanisms through which the isolated compounds contribute to these effects are still being investigated. Grandchildren are some of lifes greatest treasures. Research shows that both magnolol and honokiol are, by nature: The extract of the magnolia bark has been used for thousands of years in traditional Chinese and Japanese medicine. The bark then undergoes a process of drying and boiling before its infused into a tincture for oral consumption. Anxiety is a mental health disorder that affects mood and behavior and is often brought on by increased stress. This is how we can shift out of survival mode, and into a state of health, wellness and longevity. The bark is particularly rich in two neolignans that are believed to be responsible for its medicinal properties magnolol and honokiol (1, 2). Its other names are magnolia cortex, cucumber tree, honoki, and swamp sassafras. Magnolia bark is the bark of the Magnolia tree which is part of the Magnoliaceae family. But with proactive, natural stress management strategies, you can increase your resilience and receive lasting benefits for every area of health. One way in which honokiol may combat cancer is by helping regulate cell signaling pathways. An in vitro and in vivo study discovered that honokiol inhibits breast cancer cells from growing and could boost the effects of other drugs used against breast cancer. In a sleep study, honokiol was able to shorten the time it took for mice to fall asleep and increased the amount of time spent asleep. Before supplementing with magnolia bark, check with your medical provider to discuss proper dosage levels and ensure theres no risk of potential interactions with any medications youre taking. For digestive problems, magnolia bark. Although commonly found in traditional Chinese and Japanese medicine, magnolia bark was also traditionally used in Native American medicine. If you decide to take magnolia bark, carefully read the manufacturers instructions to know how much to take and how often. Other common names include Cucumber Tree, Magnoliae cortex, Swamp Sassafras, Houpo, and Honoki. Both shade and ornamental tree, the California sycamore is large and grows fast, so make sure that you have enough space in your property. The supplement has been used in traditional Chinese medicine for thousands of years, and current research has confirmed that magnolia bark has many potential benefits for humans. Honokiol: When stress and anxiety overwhelm your mind and your life, honokiol a compound extracted from magnolia bark offers quick, calming relief. MAGNOLIA BARK MAY HELP SUPPORT RELAXATION AND STRESS MANAGEMENT* One of main Magnolia Bark benefits is its unique calming effects. Phellodendron is used for osteoarthritis, weight loss and obesity, diarrhea, ulcers in the stomach or upper part of the small intestine (peptic ulcers), diabetes, meningitis, pneumonia, eye infections, tuberculosis, and cirrhosis of the liver. Magnolia bark is an unapproved substance without clinical data to back up the claims of traditional practitioners. Allenstown, NH. In a trial involving Magnolia officinalis extract (MOE), stomach ulcers in mice were healed after receiving 30-120mg daily of the extract. Go for a walk in the woods, dip your feet in the ocean, or relax on a hammock in your backyard. One fascinating new study demonstrated that after 60 days of daily meditation practice, galectin-3 levels among heart disease patients were significantly reduced, compared to their original baseline. Luckily, a large and fast-growing body of research has given us a specific therapeutic target to achieve this goal: the biological protein galectin-3. Related: Stress Hormones: How Diet Affects Hormonal Balance. Below are the top researched-backed magnolia bark benefits for health. Magnolia bark for anxiety. Today, magnolia bark extract is used all over the world and forms a key ingredient in many beauty products and food supplements. The extract was able to regulate protein levels in the brain that are indicative of anxious behavior. Along with increasing your overall resilience, MCP blocks galectin-3, the alarm protein that triggers inflammation and causes many of the harmful effects associated with chronic stress. And while stress is unavoidable now more than ever you can take steps to help your body respond in a healthier way. A study in mice found a magnolol dose of 2.30.9 mg per pound (525 mg per kg) of body weight significantly decreased sleep latency, or the amount of time it takes to fall asleep (27). And part of that means better understanding galectin-3. Those reactions protect you when youre facing immediate, temporary threats like avoiding a car crash. Phenolic constituents from the stem bark of Magnolia officinalis. When we address galectin-3, we see enhanced results when we layer additional therapies that work synergistically with this approach. In cancer, its a primary conductor. The bark of the magnolia . Magnolia. Consider alternative sleep herbs that are harvested in a more sustainable manner. These responses are a natural part of our immediate survival drive, but over time, they fuel inflammation, degeneration and cancer progression. The Extraordinary Importance of Sleep: The Detrimental Effects of Inadequate Sleep on Health and Public Safety Drive an Explosion of Sleep Research. There are so many ways that chronic stress harms your body, mind, and mood. All Rights Reserved. Note that the numbers in parentheses (1, 2, etc.) The herb combination reduced salivary cortisol, a marker of stress, by 18% in comparison to the placebo. Identification of Magnolia officinalis L. bark extract as the most potent anti-inflammatory of four plant extracts. We increase our longevity and health-span significantly, by balancing our biochemical alarm system. New patients are welcome. It may also possess anti-cancer effects in higher doses. Traditional Chinese Medicine (TCM) is an ancient form of healthcare that dates 7 Natural Ways to Relieve Stress & Calm Down Your Anxiety, Stress Hormones: How Diet Affects Hormonal Balance, clinically researched modified citrus pectin (MCP), Frankincense Essential Oil Uses and Benefits for Healing, Oregano Oil Benefits for Infections, Fungus & Even the Common Cold, L-Glutamine Benefits Leaky Gut & Metabolism, Secret Detox Drink Recipe (A Natural Detox Drink Recipe), Chia Seeds Benefits: The Omega-3, Protein-Packed Superfood, Apple Cider Vinegar Benefits for Weight Loss, Skin Health, Cholesterol & More, Symptoms of Candida Overgrowth & How to Get Rid of It, Investing in Your Grandkids Future? This formulation has 65+ studies showing results. During the 7th century, monks in the Chinese Buddhist temples grew these trees in their gardens for use in treating conditions like depression, asthma, muscle pain, and headache. The extract also made the mouses fur glossier and improved bowel movement regularity. Both the root and branch bark are used in therapeutic medicine. Magnolia bark is not on the United Plant Savers at-risk list (sensitive to the impact of human activities). Currently, there are no official recommendations for magnolia bark dosage. Nevertheless, additional research in humans is needed. For more than 30 years, Ive specialized in the integrative treatment of cancer, designing individualized protocols that combine diverse modalities into a comprehensive care plan based on each patients unique story. Journal of the International Society of Sports Nutrition, 10(1), 37. https://doi.org/10.1186/1550-2783-10-37, Tian, H., Zhao, L., Zhang, Q., Zhang, Y., Mao, X., Wang, J., Li, T., Li, J., You, Z., Ruan, Q., & Jiang, L. (2020). Not recommended for use during pregnancy and breastfeeding due to lack of data and evidence. Doing so may cause drowsiness and make it unsafe for you to drive or use heavy machinery., Alternative Therapies in Health and Medicine: Effect of a proprietary Magnolia and Phellodendron extract on weight management: a pilot, double-blind, placebo-controlled clinical trial., Current Microbiology: The Therapeutic Effects ofMagnolia Officinalis Extraction on an Antibiotics-Induced Intestinal Dysbacteriosis in Mice., Institute for Traditional Medicine: MAGNOLIA BARK., Journal of the International Society of Sports Nutrition: Effect ofMagnolia officinalis andPhellodendron amurense (Relora) on cortisol and psychological mood state in moderately stressed subjects., Journal of Zhejiang University. https://doi.org/10.1211/0022357001777432, Lloyd & Lloyd (1887). Researchers go on to mention that there were no toxic effects associated with honokiol. (2008). Magnolia bark ( Houpu) is a traditional Chinese herb that has been used to aid sleep for thousands of years . 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