Bottom Line Potassium Gluconate vs Potassium Chloride The main differences between the two medicines are that the KCI is given if there are low levels of both chloride and potassium in the blood, while KG is given to patients as a supplement if he has a healthy chloride level. With medications or additives that contain potassium, you may need to adjust your diet. WebWhat is the difference in potassium gluconate, chloride, citrate? Am I choosing an appropriate replacement? Philadelphia: W.B. Do not keep outdated medicine or medicine no longer needed. 1985 Sep;79(3):284-8. doi: 10.1016/0002-9343(85)90305-5. Increasing dietary potassium (and alkali) intake by increasing fruit and vegetable intake or by taking potassium bicarbonate (KHCO3) supplements has been found to decrease urinary calcium excretion. 1995;268(4 Pt 2):R825-837. For oral dosage form (liquid for solution): Adults and teenagers20 milliequivalents (mEq) mixed into one-half glass of cold water or juice, taken two to four times a day. Water, electrolytes, and acidBase Metabolism In: Ross AC, Caballero B, Cousins RJ, Tucker KL, Ziegler TR, eds. I read an Article on a pharmaceutical blog comparing potassium gluconate to POT chloride. It can sometimes be difficult to understand the difference in potassium products, as we are dealing with different units of measure (mEq vs. mg) and different salt forms (chloride vs. gluconate). Get answers from Nephrologists and top U.S. doctors, Our doctors evaluate, diagnose, prescribe, order lab tests, and recommend follow-up care. Potassium chloride and potassium gluconate are both used to treat and prevent hypokalemia. One of the main reasons potassium drops too low, regardless of diet, is due to the medications patients are taking, most notably diuretics. Certain other medications as well are known to cause potassium loss including many drugs used in the treatment of cancer. Nutr Today. Epub 2022 May 8. 2013 Aug 15;305(4):F592-9. Two additional meta-analyses published in 2017 also confirmed a blood pressure-lowering effect of supplemental potassium. Potassium Citrate rated 8.0/10 vs Potassium Gluconate rated 0.0/10 in overall patient satisfaction.The Potassium Chloride is to increase your potassium WebPOTASSIUM GLUCONATE (poe TASS i um GLOO koe nate) prevents and treats low levels of potassium in your body. Potassium gluconate has been reported to be better tasting, and easier to swallow than potassium chloride products. Imran Dosani answered. From retail, clinical, program development, and administrative responsibilities, he's your knowledgeable and go-to source for all your pharmacy and medication-related questions! In general, the daily minimum requirement for intake of potassium is 3,000 to 3,750 mg per day, or 30-40 mEq/day. WebPotassium chloride tastes similar to sodium chloride (table salt), potassium citrate is tart, potassium gluconate is basically tasteless. The FNB did not find sufficient evidence to determine an Estimated Average Requirement (EAR) and derive a Recommended Dietary Allowance (RDA); instead, they established an adequate intake (AI) based on median intakes in generally healthy people (Table 1) (9). June 26, 2018. Electrolyte imbalance (high or low sodium, chloride, or carbon dioxide in the blood) or Heart disease or Kidney diseaseUse with caution. 5. (PubMed), 32. Adler AJ, Taylor F, Martin N, Gottlieb S, Taylor RS, Ebrahim S. Reduced dietary salt for the prevention of cardiovascular disease. Macdonald HM, Black AJ, Aucott L, et al. Take this medicine only as directed by your doctor. The alkaline characteristics may help in those with metabolic acidosis, or in those susceptible to kidney stones. Potassium Chloride contains more elemental potassium than potassium gluconate. 307 Linus Pauling Science Center For these, please consult a doctor (virtually or in person). Created for people with ongoing healthcare needs but benefits everyone. Feel free to send him an email at Hello@HelloPharmacist.com! Studies show that magnesium lowers cholesterol in total by approximately 12% and LDL specifically by as much as 18%. The results of magnesium ingestion on lowering bad cholesterol levels are quite similar to the effects of statin-based drug therapy. Disclaimer. One milliequivalent (mEq) or one millimole (mmol) corresponds to about 39 mg of potassium. Potassium chloride is 52% potassium by mass while potassium gluconate contains 16.7% elemental potassium by mass. Available for Android and iOS devices. 1. Alternatively, potassium bicarbonate supplementation might decrease urinary acid and calcium excretion and influence bone turnovera small trial in postmenopausal women found that potassium bicarbonate supplementation increases biomarkers of bone formation and a decreased biomarkers of bone resorption (27). Your doctor may change the dose if needed. It is important to discuss your options with your doctor as there are a variety of factors that need to be taken into consideration in regards to regaining normal potassium levels. Potassium chloride can cause confusion, anxiety, uneven heartbeat, thirst, muscle weakness, nausea or numbness. Therefore, if your potassium gluconate supplement contains 550 mg, it only contains around 91 mg of elemental potassium. Lamisil Vs. Lotrimin: What Is The Difference? Conductivity in water (piezo buzzer) Potassium Chromate NONE. Nancy Williams has been writing about health-related topics since 1979. 2016;5(10). include protected health information. Association between urinary sodium and potassium excretion and blood pressure among adults in the United States: National Health and Nutrition Examination Survey, 2014. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. 2013;4(3):368s-377s. Dion M, Ankawi G, Chew B, Paterson R, Sultan N, Hoddinott P, Razvi H. Can Urol Assoc J. The solution should be well mixed in water or juice. Its formula is: c6h11ko7. Potassium chloride is used as a supplement to raise potassium levels in your body. Hypokalemia is most commonly a result of excessive loss of potassium, e.g., from prolonged vomiting or diarrhea, use of some diuretics and other medications (see Drug interactions), some forms of kidney disease, or metabolic disturbances. Osteoporos Int. Do not double doses. A meta-analysis of randomized controlled studies showed that heart rate in healthy adults was unlikely to be affected by the chronic use of supplemental potassium doses of 2 to 3 g/day (52). (PubMed), 45. However, most people will not take more than 100 mEq a day. Potassium citrate contains potassium and citric acid, while potassium gluconate is composed of potassium and gluconic acid. Oral doses of potassium >18 g taken at one time in individuals not accustomed to high intakes may lead to severe hyperkalemia, even in those with normal kidney function (6, 50). Potassium salt can be bought from a number of retailers including Amazon, Walmart, and Instacart. Bethesda, MD 20894, Web Policies Potassium chloride is 52% elemental potassium by mass while potassium gluconate is only 16.7% elemental potassium by mass. 2015 Jul 7;87(2):105-20. doi: 10.4081/aiua.2015.2.105. If you have kidney disease, gout or kidney stones, potassium citrate is preferred because of its chemical composition 3. (PubMed), 11. If your kidneys are not functioning properly, your body may develop a dangerous level of potassium, according to Medline Plus. However, most people will not take more than 100 mEq a day. Salmon. 1997;336(16):1117-1124. Role of proximal tubule in the hypocalciuric response to thiazide of patients with idiopathic hypercalciuria. coughing up vomit which looks like coffee grounds; have hyperkalemia high levels of potassium in the blood; have Addisons disease, a long-term endocrinedisorder; some medicines for heart problems, hypertension, kidney protection; quinidine (acts as a class I antiarrhythmic agent); medicines for pain and inflammation, such as naproxen or ibuprofen; methenamine (a heterocyclic organic compound); lithium (used to treat the manic episodes of manic depression); digoxin (used to treat congestive heart failure); dextroamphetamine,amphetamine, or similar meds. (PubMed), 31. Potassium concentrations are about 30 times higher inside than outside cells, while sodium concentrations are more than 10 times lower inside than outside cells. Potassium citrate is used to treat a kidney stone condition called renal tubular acidosis. He's answered thousands of medication and pharmacy-related questions and he's ready to answer yours! 6. Am J Clin Nutr. 1997;81(3):611-639. The pharmacist compares dosing for potassium gluconate and potassium chloride as well as other differences between the two potassium salt forms. ChildrenDose must be determined by your doctor. Fenton TR, Eliasziw M, Lyon AW, Tough SC, Hanley DA. In a 2015 case-cohort study nested within the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk study, which included 5,319 individuals, dietary intakes of potassium (alone or combined with intakes of magnesium) were found to be inversely associated with heel bone (calcaneus) broadband ultrasound attenuation (BUA) measurements (a predictor of the risk of incidental fracture) and risk of hip fracture in women but not in men (23). Gijsbers L, Molenberg FJ, Bakker SJ, Geleijnse JM. Some capsules may be opened and the contents sprinkled on applesauce or other soft food. It is also used to prevent kidney stones that may occur with gout. JAMA. Do not crush or chew the capsule. Because fruit and vegetables are rich in both potassium and precursors to bicarbonate ions, increasing their consumption might help reduce the net acid content of the diet and preserve calcium in bones, which might otherwise be mobilized to maintain normal pH (see the article on Fruit and Vegetables). A 2014 meta-analysis of 17 randomized controlled trials that examined the effect of the DASH diet compared to a control diet in a total of 2,561 adults found overall reductions in systolic and diastolic blood pressure by 6.7 mm Hg and 3.5 mm Hg, respectively (39). Video chat with a U.S. board-certified doctor 24/7 in less than one minute for common issues such as: colds and coughs, stomach symptoms, bladder infections, rashes, and more. Potassium citrate contains potassium and citric acid, while potassium gluconate is composed of potassium and gluconic acid. WebPotassium citrate is an alkalizing agent. To provide you with the most relevant and helpful information, and understand which Can You Take A Z-Pak If You Have A Penicillin Allergy? I'm confused about the difference between all the different types of Mucinex products out there. Furthermore, this mineral is an important health nutrient that is good for reducing the risk of kidney stones, lowering blood pressure, reducing the risk of stroke, and increasing bone-beneficial calcium. This content does not have an Arabic version. All rights reserved. Natural Medicines. He graduated from the University At Buffalo with a Doctor of Pharmacy degree in 2010. (PubMed), 42. Potassium chloride is used as a supplement to raise potassium levels in your body. Potassium's cardiovascular protective mechanisms. Some salt substitutes can be high in potassium. (PubMed). 2010;4(2):79-89. 2015;26(4):1311-8. doi:+10.1007/s00198-014-3006-9, Chatterjee R, Slentz C, Davenport CA, et al. Long-term treatment of calcium nephrolithiasis with potassium citrate. In a more recent meta-analysis of 16 studies, the highest versus lowest dietary potassium intake was found to be associated with a 13% lower risk of stroke after multiple adjustments (including for blood pressure) (17). Am J Clin Nutr. 2018;10(9). Broccoli. Too much potassium is We answer our latest question regarding the difference between dietary potassium from foods and potassium medication to treat hypokalemia (low potassium). Potassium chloride is 52% elemental potassium by mass while potassium gluconate is only 16.7% elemental potassium by mass. The lowest risk of stroke corresponded to daily potassium intakes around 3,500 mg. Subgroup analyses showed a reduced risk of ischemic stroke, but not hemorrhagic stroke. Dietary sodium: a therapeutic target in the treatment of hypertension and CKD. 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Contains more elemental potassium than potassium chloride is used as a supplement to raise potassium in. Or additives that contain potassium, you may need to adjust your diet dangerous level of.... To answer yours do not keep outdated medicine or medicine no longer needed the... The results of magnesium ingestion on lowering bad cholesterol levels are quite to... At Hello @ HelloPharmacist.com supplement to raise potassium levels in your body may a. Additives that contain potassium, you may need to adjust your diet effects of statin-based drug therapy bad levels... By as much as 18 % preferred because of its chemical composition 3, chloride, citrate 2! Magnesium ingestion on lowering bad cholesterol levels are quite similar to the effects of drug... Gluconate to POT chloride, most people will not take more than 100 mEq day... The treatment of cancer blood pressure-lowering effect of supplemental potassium pharmaceutical blog comparing potassium gluconate is of! Loss including many drugs used in the hypocalciuric response to thiazide of patients with hypercalciuria! Daily minimum requirement for intake of potassium and gluconic acid:284-8. doi: 10.4081/aiua.2015.2.105 lowering bad cholesterol levels quite. Been reported to be better tasting, and Instacart is used as a supplement to potassium!
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