Text Years ago Noubar Afeyan, the founder of Flagship Pioneering, which backs life sciences companies such as Covid-19 vaccine maker Moderna Inc., walked into Managing Partner Doug Cole's. Flagship filed 341 patent applications in 2020, more than double the number it had filed two years earlier; in the first half of this year, it cranked out 379 patent applications. Karin Sartorius-Herbst and her sister Ulrike Baro own stakes in German biopharma outfit Sartorius AG, founded by their great-grandfather Florenz Sartorius in 1870. Noubar Afeyan (Western Armenian: ; born in 1962) is an American-Canadian entrepreneur, inventor, and philanthropist. What if red blood cells could transport drugs along with oxygen? They do, indeed; I had one. Indigo Agriculture was founded in 2013 to use microbes to make seeds more productive. Outside that is where people think its reckless to workbut thats exactly where Flagship wants to be. [1], Afeyan sits on the boards of the MIT Corporation, the Boston Symphony Orchestra,[21][22][15] and the Armenian General Benevolent Union (AGBU). His company, Flagship Pioneering, is in the business of starting other companies using a methodological set of steps. Noubar Afeyan Age : 59 Public asset : 407,545,581 USD Country of residence : Unknown Linked companies : Moderna, Inc. - Omega Therapeutics, Inc. Have you faced such criticism? Noubar Afeyan (Photo by Neilson Barnard/Getty Images for 100 LIVES) Noubar Afeyan was born to Armenian parents in Lebanon. Hes very provocative and very challenging and very demanding, says Simba Gill, CEO of Evelo Biosciences, a Flagship company focused on the microbiome, who first met Afeyan more than two decades ago. They set us up on the path to success. . I have written two books about Mahler, in 1987 and 2010. He is the founder and chairman of Hyderabad-based drugmaker MSN Group, which started producing a low-cost version of the Covid-19 antiviral favipiravir in August. Flagship currently holds 20.5 million shares of Moderna worth $6.6 billion after selling off $3.4 billion according to their SEC Filing 13-F. As per our form 4 filing, this program covered 10 million shares, and is now concluded. Dr. Noubar Afeyan, 58, is co-founder and chairman of the biotech company Moderna. Noubar is a member of the Corporation of MIT (the Institute's governing body) and a member of the board of overseers for the Boston Symphony Orchestra. There he oversaw the creation of Celera Genomics. He teaches and speaks around the world on topics ranging from entrepreneurship, innovation, and economic development to biological engineering, new medicines, and renewable energy. Flagship Pioneering, a VC fund run and majority owned by Moderna chairman and cofounder Noubar Afeyan, sold $1.4 billion of shares in late February and late March. Hu Kun is the chairman of Shenzhen-listed Contec Medical Systems, which makes a range of medical equipment including pulse oximeters and pulmonary devices used to check lung conditions. The firm has "fostered the development of more than 100 scientific ventures, resulting in $20 billion in total value and over 500 patents. Exactly a year later, it is now worth $302.42. Photo by Jake Belcher. Executives at Moderna and other pharma companies that developed vaccines for Covid-19, including Pfizer and Novavax, sold a further $400 million in shares over the same time period, for a total of $1.9 billion. Gregorian is the former president of Brown University as well as the NewYork Public Library. Copyright 2021 The Armenian Mirror-Spectator. 1d ago. Lebrecht begins his book with the Communist Manifesto, published in London by Marx and Engels in 1848, and ends in 1947 with the birth pangs of the State of Israel. Together with his partners, he has launched philanthropic projects including the Aurora Humanitarian Initiative, FAST Foundation, and the UWC Dilijan School. Sure, the 59-year-old founder and CEO of "venture. Gong Yingying is the founder and chairwoman of Chinese healthcare tech firm Yidu Tech, which used its AI and big data technology to help the hard-hit city of Wuhan conduct contact tracing and coordinate its emergency response. Dr. Noubar Afeyan, 58, is co-founder and chairman of the biotech company Moderna. Benefactors of the Park from the outset, Dr. Afeyan and his wife Anna have endowed the Park's Fund for Programs. Yu De-Chao is the founder and chairman of Chinese biopharma outfit Innovent Biologics, which is developing a potential antibody treatment for Covid-19. And its not a joke. Like other Flagship companies, its also a so-called platform company, something that Afeyan argues reduces the risk of the startups in its portfolio and allows any of them to shift from one area to another as the need arises, as Moderna did with Covid-19 vaccines. Collectively, Moderna executives and Flagship funds have sold nearly $1.9 billion (pretax) of the companys fast-rising stock since March 2020. Noubar Afeyan, an immigrant from Lebanon, is the co-founder and chairman of Moderna, the company behind one of the most promising potential COVID019 vaccines. Isadore Rabi, son of Russian migrs, credited his mom with his Nobel Prize in physics. I am the first generation in my family to go to college. Founded in 2000, Flagship is an enterprise where entrepreneurially-minded scientists invent seemingly unreasonable solutions to challenges facing human health and sustainability. . Lpez-Belmonte Lpez chairs Spanish pharma company Rovi, which inked a contract with Moderna in July to fill and package hundreds of millions of doses of its Covid-19 vaccine at Rovi's factory in Madrid, Spain. I bow to his heart, his mind and to his legacy.. Dr. Noubar Afeyan is founder and CEO of Flagship Pioneering, a company that conceives, creates, resources, and develops first-in-category life science platform companies to transform human health and sustainability. He is a Senior Lecturer at the MIT Sloan School of Management. NET WORTH: $1.9 BILLION SOURCE OF WEALTH: BIOTECH Afeyan, who became a U.S. citizen in 2008, credits being an immigrant for his willingness to take risks and go against the grain. If were going to deliver on this vision, weve got to get to the right scale, Hovsepian says. He is a Senior Lecturer at MIT's Sloan School of Management. Flagship Pioneering. Afeyan was born in Beirut and his family later moved to Montreal, Canada. It is recounted brilliantly by Norman Lebrecht, a British journalist and novelist, and graduate of Bar-Ilan University, in his book. The prospect that I wouldve been throwing away a brand-new Ph.D. going into an area that wouldve failedthat thought never occurred to me.. LEBRECH RECOUNDS the genius of such well-known figures as Marx, Freud, Einstein and Kafka. I cover the world's richest people and how they made their billions. [20], In 1988, he founded PerSeptive Biosystems and served as its CEO. This remains a long game, however, as researchers work out the science and go through clinical trials. And that's . Flagship . As Moderna shares plunge below $50 in Wednesday morning trading, I called back to my Forbes article of last week. . The next biggest seller is Bancels colleague and Modernas chief medical officer, Tal Zaks, who made $108.2 million (pretax) in sales of Moderna shares. The timeline: A vaccine in under a year. Bancel. Why Are Moderna Insiders Selling So Many Shares? Its focus: T cells, a type of white blood cells that helps protect the body from infection. He also leads the firm's VentureLabs unit that invents and launches transformative startups. He is also co-founder and Board Chairman of Moderna. Dr. Noubar Afeyan recently spoke to the Belmont Hill and Winsor communities in a webinar during which he also answered questions submitted by students. This past April, for example, Ohana Biosciences, a fertility company that focused on sperm-based treatments, shut its doors and laid off most of its staff a little over a year after emerging from stealth. Prathap Reddy is the founder and chairman of Indian hospital chain Apollo Hospitals Group, which launched more than a dozen post-Covid recovery clinics in October for patients suffering long-term effects from the disease. I am concerned here only with this specific period, 1847-1947, which was also the period of greatest creativity in human history. Dec 14, 2020, 8:59 AM. Every one of our companies is born to aspire to what Moderna has done, he told Forbes during an interview at Flagships offices overlooking the Charles River. Flagship Pioneering, a VC fund run and majority owned by Moderna chairman and cofounder Noubar Afeyan, sold the shares in late February and late March. Many founders become serial entrepreneurs, starting companies and moving on, sometimes in rapid succession. [10], Besides English, Afeyan speaks Western Armenian. Modernas chief medical officer is Dr. Tal Zaks, an Israeli who completed his M.D. He is also co-founder and Board Chairman of Moderna. But thats the way Noubar thinks, and he has stuck with it the whole time.. He sold about 1.7 million shares7% of his stakefor a combined $161.2 million (pretax) since March 2020, taking advantage of the stocks blistering rise since the onset of the pandemic. What if not all viruses were bad? By 2020, Flagship had more than doubled the pace to average of five startups a year. Through it Afeyan is churning out scientific ideas in biotech, the life sciences and agriculture with the goal of creating and nurturing a half dozen or more companies each year. Years later, as the Communist regime took over Bulgaria, the Afeyans moved again, escaping to Greece before settling in Lebanon in the early-1950s. Not every Moderna billionaire has been reducing their position, though: Founding investor Timothy Springer and cofounder Robert Langer, both professors at Harvard and MIT, respectively, also became billionaires thanks to their Moderna holdings but neither has sold a share since the company was founded in 2010. He is credited with helping to build more than 50 new startups in the science and technology industries. As Flagships researchers studied the issue, he says, they learned of a family of viruses, known as anelloviruses, that live in humans but had been largely dismissed because they werent harmful. After you read this book, it comes as no surprise that two Jews, Bourla and Zaks, are spearheading two COVID-19 vaccines to which many may one day soon owe their lives. Founded in 2000, Flagship is an enterprise where entrepreneurially-minded scientists invent seemingly unreasonable solutions to challenges facing human health and sustainability. Some vaccine companies have been so successful that their rise over the last year has minted several new billionaires from the same company, including four apiece from Moderna and Tianjin-based CanSino Biologics, which saw its one-shot vaccine approved by Chinese regulators in February. Millions of European Jews left their towns and villages and embarked on the arduous journey to the goldene medina of America (and Canada), where Jewish genius flourished. From left, Raffi Afeyan; Taleen Afeyan; Anna Afeyan, Noubar Afeyan, Alex Afeyan. There is a very low probability in the biotech industry that any one product will work, so why subject millions of dollars and years of life in one binary product?, Scale is also important to Repertoire Immune Medicines, a Flagship company run by John Cox, a biotech veteran who oversaw Bioverativ through its $11.6 billion sale to Sanofi. He has been a Senior Lecturer at MIT's Sloan School of Management where he has taught courses on technology . Noubar Afeyan Net Worth, Age, Height, Weight, Wife, Wiki, Family 2023. So far, 30 of Afeyans companies have completed the entire process. As Flagship has expanded, Afeyan has recruited a bevvy of high-powered executives to help out, both as partners of the firm and as CEOs of the new startups. NOUBAR AFEYAN, CO-FOUNDER AND CHAIRMAN, MODERNA: Great to be here, Walter. It was another to make it a process, Afeyan says. Below are key takeaways from a conversation this week around Moderna's early days, its startup DNA, immigrant leadership, and why the recent focus on a COVID-19 vaccine should not be called a pivot. He was not from the country. He also said that according the most recent statistics, 29 percent of the population of the city is foreign born. During the Armenian genocide of 1915-16, in which as many as 1.2 million Armenian Christians living in the Ottoman Empire were killed, Afeyans paternal grandfather and great uncle were taken away twice, he says. An investor today will believe the vaccine. All we are doing is running an evolutionary process, he says. [2] In total, he co-founded or helped build over 50 life science and technology startups. My kids are descendants of an Armenian father and a Swedish mother. Noubar Afeyan launched 70 companies by pushing researchers to ask what if their craziest ideas were true. Prior to founding Flagship Pioneering, Noubar was the founder and CEO of PerSeptive Biosystems, a leader in bio-instrumentation that grew to $100 million in annual revenues. Among them: Karl Landsteiner, whose research enabled physicians to transfuse blood without endangering patients lives; Paul Erlich, pioneer of chemotherapy, who found a cure for syphilis; Magnus Hershfield, among the earliest advocates for homosexual and transgender rights; and my favorite, Rosalind Franklin, whose X-ray diffraction images of DNA at Kings College, London, led Crick and Watson to their pathbreaking discovery of the DNA double helix. I interviewed Lebrecht by email. [1][2] He is best known for co-founding the biotechnology company Moderna, through his venture capital firm, Flagship Pioneering, and for co-founding humanitarian projects such as Aurora Prize and The Future Armenian. BOSTON Immigrants and their unique and vital contributions to the success of the US economy since the nation's founding were the dominant themes of a program paying tribute to Dr. Noubar Afeyan, biotech innovator and philanthropist, on Wednesday, September 18, at the InterContinental Hotel. Marty Martinez (Leo Gozbekian photo). He was always having to prove himself, says Afeyan. AboutPressCopyrightContact. Dr. Noubar Afeyan's 32-year career as an inventor, entrepreneur and CEO has . Ren Jinsheng is the founder and chairman of pharmaceuticals supplier Simcere Pharmaceutical Group, which increased its production of antiviral drugs arbidol and zanamivir in response to higher demand in the hopes they could help treat Covid-19. But this meant every Jew had to be literate, to know the Torah. He called the park as a community partner for the city, one which gives an arena to immigrants to tell their stories.. Nearly a decade after its founding, Seres has only one drug in phase 3 clinical trials and some other treatments in earlier stage trials. If you do something in parallel, you are forced to get to the essence of it, he says. The underlying cause of most autoimmune diseases is related to T-cell misbehavior, Cox explains. These are folks that come from Myanmar, Burundi, South Sudan. (Each year the two halves of the sculpture are pried apart and reconfigured in a new way, to symbolize leaving the past and creating a new life. While scientists had talked about the microbiome for years, when Afeyan first broached the idea in 2008 of exploring its role in disease, including autoimmune diseases and cancer, it was pretty far out on the fringe. Everybody loves Moderna, but [platforms] tend to be something that is in fashion or out of fashion. But Afeyan didnt care what anyone else thought. Noubars commitment to improving the human condition through science and business goes hand in hand with social investments and a global humanitarian initiative. Li Wenmei is the cofounder and general manager of diagnostic test supplier Guangzhou Wondfo Biotech, which makes a range of Covid-19 tests. Flagship Pioneering Founder & CEO Noubar Afeyan, Ph.D, reflects on some of the forces shaping biotech, the areas ripe for bold leaps, and the lessons to carry forward as we continue to grapple with the ongoing global COVID-19 pandemic. In his remarks, honoree Afeyan singled out for praise his Swedish-born wife, Anna, his partner in his philanthropic endeavors, and expressed his hopes for his four children. [3][1] By 2020 Afeyan had co-founded and developed 41 start-ups. Modernas fifth-largest individual shareholder, president Stephen Hoge, sold $65.5 million worth of Moderna stock since March 2020; Hoges 0.4% stake in Moderna is worth roughly $300 million, but he also owns about $545 million in options. It shows that life, hope and opportunity triumph over tragedy and despair, he said. Noubar Afeyan is founder and CEO of Flagship Pioneering. [12][13], Afeyan has authored numerous scientific papers. Its chair and co-founder, Noubar Afeyan, a Beirut-born Armenian who immigrated to the U.S., had become fascinated by mRNA in 2010, when he heard a pitch from a group of Harvard and MIT researchers. What lies behind that phenomenon is what prompted me to write the book. In 2022, Noubar was elected to the National Academy of Engineering. Flagship Pioneering, a VC fund run and majority owned by Moderna chairman and cofounder Noubar Afeyan, sold $1.4 billion of shares in late February and late March. When he used to come home from school, she did not ask him what he learned that day, but rather asked, what good questions did you ask in school today, Isadore?Later, Rabis good questions helped led him to discover nuclear magnetic resonance the foundation of todays lifesaving MRI imaging devices. Shortly after the World Health Organization declared Covid-19 a global pandemic on March 11, 2020, markets collapsed and economies around the world plunged into recession. [41], Interview with Fareed Zakaria Dec. 5, 2021, "Immigrant-Founded Moderna Leading The Way In Covid-19 Response", "Moderna chairman, grandson of an Armenian genocide survivor, speaks about COVID-19 vaccine efforts and his own journey", "Meet The Lebanese Chairman Behind The Vaccine Company With 94% Effectiveness", "In His Spare Time, Immigrant Noubar Afeyan Has Started 38 Companies In America", "Meet Moderna's cofounder and chairman, whose coronavirus vaccine could roll out nationwide as soon as this weekend. They have four children. Beyond his stake in Moderna, he also owns shares in more than a dozen publicly traded biotech companies in the U.S. He became chief business officer of Applera, the successor company to Perkin-Elmers life sciences business, but was soon thinking about his next move. Consider Flagships work in the microbiome, the flourishing microorganisms that live within us, especially in our guts. Was it perhaps because of your book about the Jewish composer Gustav Mahler? In 2020, Afeyan was recognized as one of four immigrants leading the efforts to find a vaccine for COVID-19. I thought I didnt have much of a downside, he says. BOSTON Immigrants and their unique and vital contributions to the success of the US economy since the nations founding were the dominant themes of a program paying tribute to Dr. Noubar Afeyan, biotech innovator and philanthropist, on Wednesday, September 18, at the InterContinental Hotel. Others got rich making everything from personal protective equipment and diagnostic tests to antibody treatments and software that helps authorities schedule vaccination campaigns, which will be essential in reopening economies and returning to normal life. "We didn't have . Throughout the evening, the phrase coming together on common ground was stressed. 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